Multiple Sclerosis Research Today is a free monthly online journal that collates and summarizes the latest research about Multiple Sclerosis, including details on diagnosis, symptoms, treatment, prognosis.

Cortical lesions and brain atrophy in MS.

Kutzelnigg A, Lassmann H

Department of Neuroimmunology, Center for Brain Research Medical University of Vienna, Spitalgasse 4, 1090 Vienna, Austria.

Multiple sclerosis is generally considered a disease of the white matter. However, this is only one pathological aspect of the disease as demyelination is prominent in the grey matter of deep cerebral nuclei and the cerebral cortex. In this review, we discuss the possibility that disease involvement of grey matter structures may significantly contribute to clinical disability in multiple sclerosis patients.

Published 13 June 2005 in J Neurol Sci, 233(1): 55-9.
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